Anandakanda 2.1.78

2.1.78

karoti kuṣṭhaṃ tāpaṃ ca śuddhihīnā manaḥśilā /
<manaḥśilāśuddhiḥ>
ajāmūtraistryahaṃ pacyāddolāyantre manaḥśilām //

cutaneous disease, and fever are caused by realgar devoid of purification.
[Purification of realgar:]
One should cook realgar for three days in goat urine using a dolāyantra;