Ashtangasamgraha 23.36

23.36

vīryavadbhāvitaṃ samyak svarasairasakṛllaghu |

rasagandhādisampannaṃ kāle jīrṇe ca mātrayā |

ekāgramanasā yuktaṃ bhaṣajyamamṛtāyate ||

aṣṭāṃśaśeṣitarasena punaśca tena prasthaṃ ghṛtasya vipacet picubhāgakalkaiḥ ||

Potent, thoroughly macerated repeatedly with fresh juices, light, / endowed with taste, smell, and the rest, taken in appropriate measure at the proper time after food is digested / and administered with a concentrated mind, medicine acts like nectar.
And with that liquid reduced to one-eighth, one should cook again a prastha of ghee with pastes measured in picu units.