The Compendium of Caraka 1.10.14

1.10.14

nimittapūrvarūpāṇāṃ rūpāṇāṃ madhyame bale /
kālaprakṛtidūṣyāṇāṃ sāmānye 'anyatamasya ca //

When causes, prodromes, and symptoms are of moderate strength;
when there is similarity with any one among time, constitution, and affected tissue;