The Compendium of Caraka 1.12.8_2

1.12.8_2

kupitastu khalu śarīre śarīraṃ nānāvidhairvikārairupatapati balavarṇasukhāyuṣāmupaghātāya&, mano vyāharṣayati&, sarvendriyāṇyupahanti, vinihanti garbhān vikṛtimāpādayatyatikālaṃ vā dhārayati, bhayaśokamohadainyātipralāpāñjanayati, prāṇāṃścoparuṇaddhi /

When vitiated, however, in the body, it afflicts the body with various disorders to the destruction of strength, complexion, happiness, and lifespan; it agitates the mind; it impairs all the senses; it destroys fetuses, causes their deformity, or retains them beyond the proper time; it engenders fear, grief, confusion, wretchedness, and excessive delirium; and it obstructs the vital breaths.