The Compendium of Caraka 1.15.10

1.15.10

madanaphalakaṣāyamātrāpramāṇaṃ tu khalu sarvasaṃśodhanamātrāpramāṇāni ca pratipuruṣamapekṣitavyāni bhavanti yāvaddhi yasya saṃśodhanaṃ pītaṃ vaikārikadoṣaharaṇāyopapadyate na cātiyogāyogāya tāvadasya mātrāpramāṇaṃ veditavyaṃ bhavati //

The measure of the dose of madanaphala decoction, indeed, and the measure of the dose of all cleansing procedures, must be determined with respect to each individual person; for that amount which, when drunk by a person, serves to eliminate the morbid doṣas and does not lead to excessive action or deficient action, should be known as the measure of his dose.