The Compendium of Caraka 1.15.24

1.15.24

yathā prayojyā mātrā yā yadayogasya lakṣaṇam /
yogātiyogayoryacca doṣā ye cāpyupadravāḥ //

How and what dose should be administered; what the sign of deficient action is, / and what belongs to proper action and excessive action; what the faults and complications are;