The Compendium of Caraka 1.25.49_7

1.25.49_7

saṃyogasaṃskrāradeśakālamātrādayaśca bhāvāsteṣāṃ teṣāmāsavānāṃ te te samupadiśyante tattatkāryamabhisamīkṣyeti //

And factors such as combination, processing, region, season, and dose are taught for each of those fermented liquors with a view to each specific effect.”