The Compendium of Caraka 3.2.13_4

3.2.13_4

āmapradoṣajānāṃ punarivikārāṇāmapatarpaṇenaivoparamo bhavati, sati tvanubandhe kṛtāpatarpaṇānāṃ vyādhīnāṃ nigrahe nimittaviparītamapāsyauṣadhamātaṅkaviparītamevāvacārayedyathāsvam/

Furthermore, disorders arising from the severe disorder of āma cease only through reducing therapy; but if persistence remains after reducing therapy has been performed, in checking the diseases one should put aside medicine opposed to the cause and administer [medicine] opposed to the disease itself, as appropriate.