The Compendium of Caraka 3.3.23_1

3.3.23_1

ye luptadharmāṇo dharmādapetāste guruvṛddhasiddharṣipūjyānavamatyāhitānyācaranti; tatastāḥ prajā gurvādibhirabhiśaptā bhasmatāmupayānti prāgevānekapuruṣakulavināśāya, *niyatapratyayopalambhādaniyatāścāpare//

Those whose righteousness is lost, who have departed from righteousness, disregard their teachers, elders, accomplished beings, ṛṣis, and venerable ones, and practice harmful deeds. Then those people, cursed by their teachers and the rest, are reduced to ashes, primarily causing the destruction of many families of men, because of the arrival of predetermined causes, while others are non-predetermined.