The Compendium of Caraka 3.3.4

3.3.4

dṛśyante hi khalu saumya nakṣatragrahagaṇacandrasūryānilānalānāṃ diśāṃ &cāprakṛtibhūtānāmṛtuvaikārikā bhāvāḥ, acirādito bhūrapi ca na yathāvadrasavīryavipākaprabhāvamoṣadhīnāṃ pratividhāsyati, tadviyogāccātaṅkaprāyatā niyatā/

"Indeed, gentle one, unseasonal morbid manifestations of the stars, planetary bodies, moon, sun, winds, and fires, as well as of the directions, are seen to have become abnormal. Soon after this, the earth also will not properly yield the taste, potency, post-digestive effect, and specific action of the medicinal herbs; and from their loss, a predominance of disease is certain.