The Compendium of Caraka 3.5.8

3.5.8

tatra prāṇavahānāṃ srotasāṃ hṛdayaṃ mūlaṃ mahāsrotaśca, praduṣṭānāṃ tu khalveṣāmidaṃ viśeṣavijñānaṃ bhavati; tadyathā---atisṛṣṭamatibaddhaṃ kupitamalpālpamabhīkṣṇaṃ vā saśabdaśūlamucchvasantaṃ dṛṣṭvā prāṇavahānyasya srotāṃsi praduṣṭānīti vidyāt/

Among these, the heart and the great channel are the root of the channels carrying breath; and when these are vitiated, this is their specific diagnostic knowledge; namely: seeing one breathing out excessively, in an excessively obstructed manner, agitatedly, in minute amounts, frequently, or with noise and pain, one should know that his channels carrying breath are vitiated.