The Compendium of Caraka 4.1.105

4.1.105

jñātānāṃ svayamarthānāmahitānāṃ niṣevaṇam/
paramaunmādikānāṃ ca pratyayānāṃ niṣevaṇam//

indulgence in objects known by oneself to be harmful, / and indulgence in causes that are supremely productive of insanity;