The Compendium of Caraka 6.17.12

6.17.12

āmapradoṣādānāhādraukṣyādatyapatarpaṇāt/
daurbalyānmarmaṇo ghātāddvandvācchuddhyatiyogataḥ//

from the disorder of āma, abdominal distension, dryness, excessive emaciation;
from debility, trauma to a vital organ, dual conflict [of seasons or regimens], and excessive cleansing;