Bhagavatapurana 1.5.33

1.5.33

āmayo yaśca bhūtānāṃ jāyate yena suvrata /
tadeva hyāmayaṃ dravyaṃ na punāti cikitsitam //

33-34. O sage of commendable austerities, it is true that in the case of living beings the very stuff which produces a particular disease, cannot also remedy it; but when medicated in composition with other things it may become a cure; similarly, in the case of men, all the *karmas* (the courses of duties) lead to Samsara; but they may themselves become the means of obtaining freedom from the sphere of duties, when they are performed and offered to the Supreme Lord as acts done in His worship.