The Compendium of Kāśyapa 8.3.12

8.3.12

vibhajya vayasastritvaṃ kathaṃ mātrā vidhīyate
adhobhāgordhvabhāgānāṃ doṣasaṃśamanī ca yā

Dividing the three stages of life, how is the dosage prescribed / for downwards-clearing, upwards-clearing, and for that which pacifies the humours;