The Compendium of Caraka 1.10.6

1.10.6

idaṃ ca& naḥ pratyakṣaṃ---yadanātureṇa bheṣajenāturaṃ cikitsāmaḥ&, kṣāmamakṣāmeṇa, kṛśaṃ ca durbalamāpyāyayāmaḥ, sthūlaṃ medasvinamapatarpayāmaḥ, śītenoṣṇābhibhūtamupacarāmaḥ, śītābhibhūtamuṣṇena, nyūnān dhātūn pūrayāmaḥ, vyatiriktān hrāsayāmaḥ, vyādhīn mūlaviparyayeṇopacarantaḥ samyak prakṛtau sthāpayāmaḥ; teṣāṃ nastathā kurvatāmayaṃ bheṣajasamudāyaḥ kāntatamo bhavati //

And this is directly perceptible to us: that we treat the sick person with health-promoting medicine; we nourish the emaciated and weak with non-emaciating measures; we deplete the obese and fatty; we treat one overcome by heat with cold, and one overcome by cold with heat; we replenish deficient tissues; we reduce excessive ones; treating diseases by counteracting their cause, we properly establish them in their natural state. When we act in this way, this collection of medicine becomes exceedingly pleasing to them.