The Compendium of Caraka 1.11.46

1.11.46

tatra buddhimatā mānasavyādhiparītenāpi satā buddhyā hitāhitamavekṣyāvekṣya dharmārthakāmānāmahitānāmanupasevane hitānāṃ copasevane prayatitavyaṃ, na hyantareṇa loke trayametanmānāsaṃ kiṃcinniṣpadyate sukhaṃ vā duḥkhaṃ vā; tasmādetaccānuṣṭheyaṃ --- &tadvidyānāṃ copasevane prayatitavyam, ātmadeśakulakālabalaśaktijñāne yathāvacceti //

Therein, an intelligent person, even when afflicted with mental disease, having repeatedly observed what is wholesome and unwholesome with his intellect, should strive for non-indulgence in unwholesome virtue, wealth, and desire, and for indulgence in wholesome ones; for in this world, without these three, no mental pleasure or pain is produced. Therefore, this is to be practiced: one should strive to associate with those knowledgeable in that, and to know properly oneself, place, family, time, strength, and capacity.