The Compendium of Caraka 1.25.29

1.25.29

yeṣāmeva hi bhāvānāṃ saṃpat saṃjanayennaram /
teṣāmeva vipadvyādhīnvividhānsamudīrayet //

For the very perfection of those factors which produces man, / the impairment of those very [factors] will give rise to various diseases.”