The Compendium of Caraka 1.28.7_6

1.28.7_6

śarīrāṇi cātisthūlānyatikṛśānyaniviṣṭamāṃsaśoṇitāsthīni durbalānyasātmyāhāropacitānyalpāhārāṇyalpasattvāni ca bhavantyavyādhisahāni viparītāni punarvyādhisahāni /

And bodies that are excessively obese, excessively emaciated, whose meat, blood, and bones are not well-established, that are weak, nourished on unwholesome food, eating little food, and of little mental strength, cannot endure disease; those of the opposite nature, on the other hand, can endure disease.