The Compendium of Caraka 2.3.5

2.3.5

tamuvāca bhagavānātreyaḥ---samutthānapūrvarūpaliṅgavedanopaśayaviśeṣebhyo viśeṣavijñānaṃ gulmānāṃ bhavatyanyeṣāṃ ca rogāṇāmagniveśa! tattu &khalu gulmeṣūcyamānaṃ nibodha//

The venerable Ātreya said to him: 'O Agniveśa, the distinguishing knowledge of gulmas as well as of other diseases arises from the specific differences in their etiology, premonitory symptoms, signs, pains, and therapeutic suitability. Listen to that as it is declared regarding gulmas.