The Compendium of Caraka 6.12.90

6.12.90

visrāvaṇaṃ piṇḍikayopanāhaḥ pakveṣu caiva vraṇavaccikitsā/
visphoṭakāḥ sarvaśarīragāstu &sphoṭāḥ sarāgajvaratarṣayuktāḥ//

Bloodletting, poulticing with a lump [of medicaments], and in the suppurated ones, treatment like a wound [should be done]; / but visphoṭakas are blisters spreading over the whole body, accompanied by redness, fever, and thirst.